Malaria affects more than 247 million people throughout the world and may have caused up to 620,000 deaths in 2021. Under the ROAdMAP project¹, Ana Gomes and her team at the Laboratory of Pathogens and Host Immunity² in Montpellier (southern France) are seeking to understand how the parasite responsible for this disease replicates its DNA, in a bid to discover any weaknesses that could be exploited as new therapeutic strategies.